Hydatidosis in Algeria

 

Pr B.Hamrioui

 

In Algeria hydatidosis with Echinococcus granulosus constitutes a real problem of

public health and animal health is also an economic problem.

– The diagnosis of human cystic echinococcosis is based on arguments

epidemiological, paraclinical and biological. Different serological techniques have been

tested and compared in the indirect diagnosis of hydatidosis. The results are obtained according to the location, the state and the number of cysts. At least 2 techniques are

used routinely.

– Biochemical studies of hydatid liquid have been made on different batches of

hydatid fluid taken from man and various animals and from all organs

parasites.

– The major and immunogenic fraction 5 (antigen 5) has been purified from the liquid

hydatid. The physico-chemical characters of this fraction have been determined. This one is

reveals to be a glycolipoprotein.

– Monoclonal antibodies have been produced against fraction 5. This opens up

broad perspectives in the various fields, both diagnostic and therapeutic.

– To fully understand the fertility problem of metacestodes from patients with

hydatidosis, long-term work is undertaken.

– A molecular characterization of Echinococcus granulosus sensu stricto and

of Echinococcus canadensis in humans and cattle in Algeria was conducted for the purpose of

to list the circulating Echinococcus granulusosus s.l strains infecting humans

Algeria. For this purpose identification by P.C.R sequencing of mitochondrial genes from a wide

panel of human strains d. E. granulosus sl and herbivorous animals was used.

– For therapeutic purposes, white mice received intraperitoneal injection

scolex collected from animal hydatid cysts several anthelmintics have
have been tested in the treatment of hydatid cyst secondary to inoculation. The variation of the

albeldazole sulfonyde concentration in the serum, the membrane is hydatid fluid as a function of time was determined.